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Abstract Details
The persistence of underreporting of hepatitis C as an underlying or contributing cause of death, 2011-2017
Clin Infect Dis. 2021 Feb 9;ciab108. doi: 10.1093/cid/ciab108. Online ahead of print.
Philip R Spradling1, Yuna Zhong1, Anne C Moorman1, Loralee B Rupp2, Mei Lu2, Eyasu H Teshale1, Mark A Schmidt3, Yihe G Daida4, Joseph A Boscarino5, Stuart C Gordon26
Author information
1Division of Viral Hepatitis, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA.
2Henry Ford Health System, Detroit, MI, USA.
3The Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
4The Center for Integrated Health Research, Kaiser Permanente Hawaii, Honolulu, HI, USA.
5Department of Population Health Sciences, Geisinger Clinic, Danville, PA, USA.
6Wayne State University School of Medicine, Detroit, MI, USA.
Abstract
Using electronic health records, we found that hepatitis C reporting on death certificates of 2,901 HCV-infected decedents from four U.S. healthcare organizations during 2011-2017 was documented in only 50% of decedents with hepatocellular carcinoma and less than half with decompensated cirrhosis. National figures likely underestimate the U.S. HCV mortality burden.