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PBC Disease Content  
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   Released: 2022
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PBC: Diagnosis and Current Management Strategies
41 slides
 
 
   Released: 2020
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Primary Biliary Cholangitis and Primary Sclerosing Cholangitis: Current and Emerging Treatments
48 slides
 
 
 
 
 
Abstract Library
1.Improving predictive accuracy in primary biliary cholangitis: A new genetic risk score
 

Liver Int. 2024 Apr 15. doi: 10.1111/liv.15916. Online ahead of print.

 

Alessio Gerussi 1 2, Claudio Cappadona 3 4, Davide Paolo Bernasconi 5, Laura Cristoferi 1 2 5, Maria Grazia Valsecchi 5 6, Marco Carbone 1 2, Pietro Invernizzi 1 2, Rosanna Asselta 3 4; Italian PBC Genetic Study Group
 
2.Pruritus in primary biliary cholangitis is under-recorded in patient medical records
 

BMJ Open Gastroenterol. 2024 Mar 27;11(1):e001287. doi: 10.1136/bmjgast-2023-001287.

 

Usha Gungabissoon 1, Helen T Smith 2, Robyn von Maltzahn 2, John Logie 2, Jolyon Fairburn-Beech 2, Liyuan Ma 3, Dhirishiya P 4, Ashleigh McGirr 5, Jake N Hunnicutt 3, Christopher L Rowe 6, Meghan Tierney 6, Haley S Friedler 6
 
3.Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
 

Clin Rev Allergy Immunol. 2024 Mar 30. doi: 10.1007/s12016-024-08986-4.Online ahead of print.

 

Yi Wu # 1, Qiwei Qian # 1, Qiaoyan Liu 1, Rui Wang 1, Xiting Pu 1, Yao Li 1, Huayang Zhang 1, Zhengrui You 1, Qi Miao 1, Xiao Xiao 1, Min Lian 1, Qixia Wang 1, Minoru Nakamura 2, M Eric Gershwin 3, Zhiqiang Li 4 5, Xiong Ma 6 7, Ruqi Tang 8
 
4.Primary biliary cholangitis drug evaluation and regulatory approval: Where do we go from here?
 

Hepatology. 2024 Mar 22. doi: 10.1097/HEP.0000000000000864. Online ahead of print.

 

David Ej Jones 1, Ulrich Beuers 2, Alan Bonder 3, Marco Carbone 4, Emma Culver 5, Jessica Dyson 6, Robert G Gish 7, Bettina E Hansen 8, Gideon Hirschfield 9, Rebecca Jones 10, Kris Kowdley 11, Andreas E Kremer 12, Keith Lindor 13, Marlyn Mayo 14, George Mells 15, James Neuberger 16, Martin Prince 17, Mark Swain 18, Atsushi Tanaka 19, Douglas Thorburn 20, Michael Trauner 21, Palak Trivedi 22, Martin Weltman 23, Andrew Yeoman 24, Cynthia Levy 25
 
5.Evolution of cerebrovascular imaging and associated clinical findings in children with Alagille syndrome
 

Neuroradiology. 2024 Feb 24. doi: 10.1007/s00234-024-03316-z. Online ahead of print.

 

Carmen Rosa Cerron-Vela 1, Luis Octavio Tierradentro-García 2, Zekordavar Lavadka Rimba 2, Savvas Andronikou 2 3
 
6.A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis
 

N Engl J Med. 2024 Feb 21. doi: 10.1056/NEJMoa2312100. Online ahead of print.

 

Gideon M Hirschfield 1, Christopher L Bowlus 1, Marlyn J Mayo 1, Andreas E Kremer 1, John M Vierling 1, Kris V Kowdley 1, Cynthia Levy 1, Alejandra Villamil 1, Alma L Ladrón de Guevara Cetina 1, Ewa Janczewska 1, Ehud Zigmond 1, Sook-Hyang Jeong 1, Yusuf Yilmaz 1, Yiannis Kallis 1, Christophe Corpechot 1, Peter Buggisch 1, Pietro Invernizzi 1, Maria Carlota Londoño Hurtado 1, Sandrin Bergheanu 1, Ke Yang 1, Yun-Jung Choi 1, Daria B Crittenden 1, Charles A McWherter 1; RESPONSE Study Group
 
7.Treatment in primary biliary cholangitis: Beyond ursodeoxycholic acid
 

Eur J Intern Med. 2024 Feb 2:S0953-6205(24)00037-2.doi: 10.1016/j.ejim.2024.01.030. Online ahead of print.

 

M C van Hooff 1, E Werner 1, A J van der Meer 2
 
8.Post-Transplant Management and Complications of Autoimmune Hepatitis, Primary Biliary Cholangitis, and Primary Sclerosing Cholangitis including Disease Recurrence
 

Clin Liver Dis. 2024 Feb;28(1):193-207. doi: 10.1016/j.cld.2023.07.009.Epub 2023 Aug 26.

 

Jacqueline B Henson 1, Lindsay Y King 2
 
9.Autoimmune Markers in Primary Biliary Cholangitis
 

Clin Liver Dis. 2024 Feb;28(1):93-101. doi: 10.1016/j.cld.2023.07.002.Epub 2023 Aug 17.

 

Shivani K Shah 1, Christopher L Bowlus 2
 
10.Systemic Complications of Primary Biliary Cholangitis
 

Clin Liver Dis. 2024 Feb;28(1):115-128. doi: 10.1016/j.cld.2023.07.004.Epub 2023 Aug 26.

 

Mariana Zapata 1, Hendrick Pagan-Torres 1, Marlyn J Mayo 2
 
11.Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: To what extent and under what conditions is normal alkaline phosphatase level associated with complication-free survival gain?
 

Hepatology. 2024 Jan 1;79(1):39-48. doi: 10.1097/HEP.0000000000000529. Epub 2023 Jul 3.

Christophe Corpechot 1, Sara Lemoinne 1, Pierre-Antoine Soret 1, Bettina Hansen 2 3, Gideon Hirschfield 3, Aliya Gulamhusein 3, Aldo J Montano-Loza 4, Ellina Lytvyak 5, Albert Pares 6, Ignasi Olivas 6, John E Eaton 7, Karim T Osman 7, Christoph Schramm 8, Marcial Sebode 8, Ansgar W Lohse 8, George Dalekos 9, Nikolaos Gatselis 9, Frederik Nevens 10, Nora Cazzagon 11, Alessandra Zago 11, Francesco Paolo Russo 11, Annarosa Floreani 11, Nadir Abbas 12, Palak Trivedi 13, Douglas Thorburn 14, Francesca Saffioti 14, Laszlo Barkai 14, Davide Roccarina 14, Vicenza Calvaruso 15, Anna Fichera 15, Adèle Delamarre 16, Natalia Sobenko 17, Alejandra Maria Villamil 17, Esli Medina-Morales 18, Alan Bonder 18, Vilas Patwardhan 18, Cristina Rigamonti 19, Marco Carbone 20, Pietro Invernizzi 20, Laura Cristoferi 20, Adriaan van der Meer 21, Rozanne de Veer 21, Ehud Zigmond 22, Eyal Yehezkel 22, Andreas E Kremer 23, Ansgar Deibel 23, Tony Bruns 24, Karsten Große 24, Aaron Wetten 25, Jessica Katharine Dyson 25, David Jones 25, Jérôme Dumortier 26, Georges-Philippe Pageaux 27, Victor de Lédinghen 16, Olivier Chazouillères 1, Fabrice Carrat 28 29; Global & ERN Rare-Liver PBC Study Groups
 
12.Pharmacotherapy for primary biliary cholangitis: an assessment of medication candidacy and rates of treatment
 

BMC Gastroenterol. 2024 Jan 4;24(1):18. doi: 10.1186/s12876-023-03108-4.

Nicholas MacDonald 1, Rebecca Loh 2, Jonathan M Fenkel 2, David A Sass 2, Dina Halegoua-DeMarzio 2
 
13.Primary Biliary Cholangitis: Epidemiology, Diagnosis, and Presentation
 

Clin Liver Dis. 2024 Feb;28(1):63-77. doi: 10.1016/j.cld.2023.06.005.Epub 2023 Aug 12.

 

Muhammad Salman Faisal 1, Humberto C Gonzalez 2, Stuart C Gordon 3
 
14.Primary Biliary Cholangitis: Pathophysiology
 

Clin Liver Dis. 2024 Feb;28(1):79-92. doi: 10.1016/j.cld.2023.06.006.Epub 2023 Aug 12.

 

Inbal Houri 1, Gideon M Hirschfield 2
 
15.Pharmacotherapy for primary biliary cholangitis: an assessment of medication candidacy and rates of treatment
 

BMC Gastroenterol. 2024 Jan 4;24(1):18. doi: 10.1186/s12876-023-03108-4.

 

Nicholas MacDonald 1, Rebecca Loh 2, Jonathan M Fenkel 2, David A Sass 2, Dina Halegoua-DeMarzio 2
 
16.Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: To what extent and under what conditions is normal alkaline phosphatase level associated with complication-free survival gain?
 

Hepatology. 2024 Jan 1;79(1):39-48. doi: 10.1097/HEP.0000000000000529. Epub 2023 Jul 3.

 

Christophe Corpechot 1, Sara Lemoinne 1, Pierre-Antoine Soret 1, Bettina Hansen 2 3, Gideon Hirschfield 3, Aliya Gulamhusein 3, Aldo J Montano-Loza 4, Ellina Lytvyak 5, Albert Pares 6, Ignasi Olivas 6, John E Eaton 7, Karim T Osman 7, Christoph Schramm 8, Marcial Sebode 8, Ansgar W Lohse 8, George Dalekos 9, Nikolaos Gatselis 9, Frederik Nevens 10, Nora Cazzagon 11, Alessandra Zago 11, Francesco Paolo Russo 11, Annarosa Floreani 11, Nadir Abbas 12, Palak Trivedi 13, Douglas Thorburn 14, Francesca Saffioti 14, Laszlo Barkai 14, Davide Roccarina 14, Vicenza Calvaruso 15, Anna Fichera 15, Adèle Delamarre 16, Natalia Sobenko 17, Alejandra Maria Villamil 17, Esli Medina-Morales 18, Alan Bonder 18, Vilas Patwardhan 18, Cristina Rigamonti 19, Marco Carbone 20, Pietro Invernizzi 20, Laura Cristoferi 20, Adriaan van der Meer 21, Rozanne de Veer 21, Ehud Zigmond 22, Eyal Yehezkel 22, Andreas E Kremer 23, Ansgar Deibel 23, Tony Bruns 24, Karsten Große 24, Aaron Wetten 25, Jessica Katharine Dyson 25, David Jones 25, Jérôme Dumortier 26, Georges-Philippe Pageaux 27, Victor de Lédinghen 16, Olivier Chazouillères 1, Fabrice Carrat 28 29; Global & ERN Rare-Liver PBC Study Groups
 
17.Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis
 

Aliment Pharmacol Ther. 2024 Jan;59(2):186-200. doi: 10.1111/apt.17755. Epub 2023 Oct 30.

Marlyn J Mayo 1, John M Vierling 2, Christopher L Bowlus 3, Cynthia Levy 4 5, Gideon M Hirschfield 6, Guy W Neff 7, Michael R Galambos 8, Stuart C Gordon 9, Brian B Borg 10, Stephen A Harrison 11, Paul J Thuluvath 12 13, Aparna Goel 14, Mitchell L Shiffman 15, Mark G Swain 16, David E J Jones 17, Palak Trivedi 18, Andreas E Kremer 19, Richard J Aspinall 20, David A Sheridan 21, Yvonne Dörffel 22, Ke Yang 23, Yun-Jung Choi 24, Charles A McWherter 24
 
18.Recommendations and quality criteria to improve the early diagnosis of Primary Biliary Cholangitis
 

GastroenterolHepatol. 2023Dec16:S02105705(23)004922.doi:10.1016/j.gastrohep.2023.12.002. Online ahead of print.

Álvaro Díaz-González 1, Noelia Fontanillas 2, Eva Gil-Hernández 3, Mercedes Guilabert 4, Maria-Carlota Londoño 5, Mar Noguerol 6, Fernando Pérez Escanilla 7, José J Mira 8, Manuel Santiñá 9
 
19.Seladelpar treatment reduces interleukin-31 and pruritus in patients with primary biliary cholangitis
 

Hepatology. 2023 Dec 20. doi: 10.1097/HEP.0000000000000728. Online ahead of print.

Andreas E Kremer 1, Marlyn J Mayo 2, Gideon M Hirschfield 3, Cynthia Levy 4 5, Christopher L Bowlus 6, David E Jones 7, Jeff D Johnson 8, Charles A McWherter 8, Yun-Jung Choi 8
 
20.Critical shortfalls in the management of PBC: Results of a UK-wide, population-based evaluation of care delivery
 

JHEP Rep. 2023 Oct 16;6(1):100931. doi: 10.1016/j.jhepr.2023.100931. eCollection 2024 Jan.

Nadir Abbas 1 2 3, Rachel Smith 4 5, Steven Flack 4, Vikram Bains 5, Richard J Aspinall 6, Rebecca L Jones 7, Laura Burke 7, Douglas Thorburn 8, Michael Heneghan 9, Andrew Yeoman 10, Joanna Leithead 11, Conor Braniff 12, Andrew Robertson 13, Chris Mitchell 14, Collette Thain 14, Robert Mitchell-Thain 15, David Jones 16 17, Palak J Trivedi 1 2 3 18, George F Mells 4 5, Laith Alrubaiy 19 20; UK-PBC audit group
 
21.Two Decades of Liver Transplants for Primary Biliary Cholangitis: A Comparative Study of Living Donors vs. Deceased Donor Liver Transplantations
 

J Clin Med. 2023 Oct 15;12(20):6536. doi: 10.3390/jcm12206536.

 

Esli Medina-Morales 1 2, Mohamed Ismail 1, Romelia Barba Bernal 2 3, Yazan Abboud 1, Leandro Sierra 2, Ana Marenco-Flores 2, Daniela Goyes 4, Behnam Saberi 2, Vilas Patwardhan 2, Alan Bonder 2
 
22.Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis
 

N Engl J Med. 2023 Nov 13. doi: 10.1056/NEJMoa2306185. Online ahead of print.

 

Kris V Kowdley 1, Christopher L Bowlus 1, Cynthia Levy 1, Ulus S Akarca 1, Mario Reis Alvares-da-Silva 1, Pietro Andreone 1, Marco Arrese 1, Christophe Corpechot 1, Sven M Francque 1, Michael A Heneghan 1, Pietro Invernizzi 1, David Jones 1, Frederik C Kruger 1, Eric Lawitz 1, Marlyn J Mayo 1, Mitchell L Shiffman 1, Mark G Swain 1, José Miguel Valera 1, Victor Vargas 1, John M Vierling 1, Alejandra Villamil 1, Carol Addy 1, Julie Dietrich 1, Jean-Michel Germain 1, Sarah Mazain 1, Dragutin Rafailovic 1, Bachirou Taddé 1, Benjamin Miller 1, Jianfen Shu 1, Claudia O Zein 1, Jörn M Schattenberg 1; ELATIVE Study Investigators’ Group
 
23.Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis
 

Aliment Pharmacol Ther. 2023 Oct 30. doi: 10.1111/apt.17755. Online ahead of print.

 

Marlyn J Mayo 1, John M Vierling 2, Christopher L Bowlus 3, Cynthia Levy 4 5, Gideon M Hirschfield 6, Guy W Neff 7, Michael R Galambos 8, Stuart C Gordon 9, Brian B Borg 10, Stephen A Harrison 11, Paul J Thuluvath 12 13, Aparna Goel 14, Mitchell L Shiffman 15, Mark G Swain 16, David E J Jones 17, Palak Trivedi 18, Andreas E Kremer 19, Richard J Aspinall 20, David A Sheridan 21, Yvonne Dörffel 22, Ke Yang 23, Yun-Jung Choi 24, Charles A McWherter 24
 
24.The feasibility and acceptability of an online mind-body wellness program for patients with primary biliary cholangitis
 

Can Liver J. 2023 Oct 30;6(3):314-331. doi: 10.3138/canlivj-2022-0045. eCollection 2023 Oct.

 

Makayla Watt 1, Ashley Hyde 1, John C Spence 2, Gail M Wright 3, Shauna Vander Well 3, Emily Johnson 1, Andrew Mason 1, Magnus McLeod 4, Puneeta Tandon 1
 
25.Autoimmune liver diseases and diabetes
 

Eur J Gastroenterol Hepatol. 2023 Sep 1;35(9):938-947. doi: 10.1097/MEG.0000000000002594.Epub 2023 Jun 22.

 

Anne-Sofie H Jensen 1 2, Henriette Ytting 2 3 4, Marie Winther-Sørensen 1, Johan Burisch 2, Annika Bergquist 2 5, Lise Lotte Gluud 2 4, Nicolai J Wewer Albrechtsen 1 6
 
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