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Abstract Details
Personalized treatment of hepatitis B
Lok AS1. Clin Mol Hepatol. 2015 Mar;21(1):1-6. Epub 2015 Mar 25.
Author information
1Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA.
Abstract
There are seven approved drugs for treatment of hepatitis B. Professional guidelines provide a framework for managing patients but these guidelines should be interpreted in the context of the individual patient's clinical and social circumstances. Personalized management of hepatitis B can be applied based on prediction of the individual patient's risk of cirrhosis and hepatocellular carcinoma to guide the frequency and intensity of monitoring and urgency of treatment. It can also be applied to decisions regarding when to start treatment, which drug to use, and when to stop based on the individual patient's disease characteristics, preference, comorbidities and other mitigating circumstances.