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Abstract Details
NAFLD fibrosis score (NFS) can be used in outpatient services to identify chronic vascular complications besides advanced liver fibrosis in type 2 diabetes
Rosa Lombardi1, Lorena Airaghi2, Giovanni Targher3, Gaetano Serviddio4, Gabriele Maffi2, Alessandro Mantovani3, Claudio Maffeis5, Antonio Colecchia6, Rosanna Villani4, Luca Rinaldi7, Emanuela Orsi8, Giuseppina Pisano2, Luigi Elio Adinolfi7, Silvia Fargion2, Anna Ludovica Fracanzani2
Author information
1Department of Pathophysiology and Transplantation Ca' Granda IRCCS Foundation, Policlinico Hospital, University of Milan, Italy. Electronic address: rosa.lombardi@unimi.it.
2Department of Pathophysiology and Transplantation Ca' Granda IRCCS Foundation, Policlinico Hospital, University of Milan, Italy.
3Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University Hospital of Verona, Verona, Italy.
4Centro C.U.R.E, Dept. of Medical and Surgical Sciences, University of Foggia, Italy.
5Pediatric Diabetes and Metabolic Disorders Unit, Department of Surgical Sciences, Dentistry, and Pediatrics, and Gynaecology, University Hospital of Verona, Verona, Italy.
6Gastroenterology Unit, Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.
7Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli" Naples, Italy.
8Department of Medical Science, Endocrinology and Diabetes Unit, Ca' Granda IRCCS Foundation, Policlinico Hospital, University of Milan, Italy.
Abstract
We demonstrate in 351 diabetic patients with steatosis that NAFLD fibrosis score (NFS), a rapid and affordable score to diagnose hepatic fibrosis, identifies patients at higher risk of advanced fibrosis and vascular diabetic complications (especially peripheral neuropathy), pointing NFS as a first-line vascular and hepatic screening in diabetic patients.