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Abstract Details
Expanding the use of hepatitis C positive donors and keeping recipient safety at the forefront
Terrault NA1, Sher L2. Am J Transplant. 2019 Dec 15. doi: 10.1111/ajt.15745. [Epub ahead of print]
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Abstract
The opioid crisis, the need for more organs for all transplant candidates and the availability of effective direct acting antivirals (DAAs) for hepatitis C virus (HCV) have converged to bring transplants from HCV-viremic donors to the forefront. While use of such organs in recipients with preexisting chronic HCV is well-established, use in HCV negative patients is a newer phenomenon and requires delineation of the risks and benefits to wait-listed patients and examination of programmatic and financial requirements to ultimately inform best practices for the transplant community.