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Abstract Details
Ablation plus Transarterial Embolic Therapy for Hepatocellular Carcinoma Larger than 3?cm: Science, Evidence, and Future Directions
Lewis AR1, Padula CA1, McKinney JM1, Toskich BB1. Semin Intervent Radiol. 2019 Oct;36(4):303-309. doi: 10.1055/s-0039-1697641. Epub 2019 Oct 31.
Author information
1 Division of Interventional Radiology, Department of Radiology, Mayo Clinic, Jacksonville, Florida.
Abstract
Thermal ablation is widely regarded as definitive therapy for early-stage hepatocellular carcinoma, but its efficacy decreases in tumors greater than 3 cm. Extensive clinical studies have supported improved outcomes provided through combining transarterial embolic therapy with ablation in the treatment of larger tumors. This article will provide a survey of the science and data for combination therapy in both thermal and nonthermal ablation modalities, as well as describe emerging applications.