Author information
1 College of Health and Life Sciences, Department of Life Sciences, Institute of Environment, Health and Societies, Division of Biosciences, Brunel University London, Uxbridge, UB8 3PH, United Kingdom.
2 Cell Signaling and Cancer Laboratory, Leeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Beckett Street, Leeds, LS9 7TF, United Kingdom.
Abstract
Accumulation of fat in liver cells not due to alcohol abuse is the hallmark of non-alcoholic fatty liver disease (NAFLD), a common condition that may progress to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation.(1) Over a long period of time, NASH may lead to fibrosis with consequent cirrhosis, which in turn predisposes patients to hepatocellular carcinoma.