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Abstract Details
Gender disparity in HCC: Is it the fat and not the sex?
1 Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch and National Cancer Institute Center for Cancer Research Liver Cancer Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD tim.greten@nih.gov.
Abstract
Men are more likely to develop hepatocellular carcinoma (HCC) than women, but it is not clear why. In this issue of JEM, Manieri et al. (https://doi.org/10.1084/jem.20181288) identify reduced adiponectin levels as responsible for the increased incidence of HCC in males.