Author information
1 Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, USA.
2 Director, Hepatobiliary Pathology, Department of Pathology, Cleveland Clinic, Cleveland, OH, USA.
3 Associate Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
4 Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, USA. mcculla@ccf.org.
5 Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
Abstract
Staging of liver fibrosis is increasingly done using noninvasive methods, in some cases obviating the need for liverbiopsy. Scores based on laboratory values and demographic variables have been developed and validated for assessing fibrosis in patients with hepatitis C virus (HCV) infection and nonalcoholic fatty liver disease (NAFLD), as have several imaging methods that measure shear-wave velocity, a reflection of fibrosis severity.