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Abstract Details
Prior Bariatric Surgery in Liver Transplant Candidates: Unforeseen Consequences?
Sharpton SR1, Terrault NA1. Liver Transpl. 2018 Dec 26. doi: 10.1002/lt.25401. [Epub ahead of print]
Author information
1
Department of Medicine, Division of Gastroenterology, University of California, San Francisco, San Francisco, CA.
Abstract
In the United States, bariatric surgeries for obesity-related complications increased from 158,000 in 2011 to 228,000 in 2017.(1) As obesity rates continue to rise, this trend can be expected to continue since bariatric surgery is the only therapeutic intervention shown to yield durable weight loss, remission of obesity-related comorbidities, and improved all-cause mortality.(2) Importantly, for those with nonalcoholic fatty liver disease (NAFLD) as a component of obesity-related complications, bariatric surgery results in histologic improvement and reduced likelihood of NAFLD progression.(3) Despite these recognized benefits, the positive and negative consequences of prior bariatric surgery on wait-list and post-liver transplantation (LT) outcomes is understudied.