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Abstract Details
Hepatitis C genotype change after transplantation utilizing hepatitis C positive donor organs
Adekunle R1, Jonchhe S2, Ravichandran B2, Wilson E3, Husson J3. Transpl Infect Dis. 2018 May 24:e12925. doi: 10.1111/tid.12925. [Epub ahead of print]
Author information
1
Department of Medicine, University of Maryland Medical Center, Baltimore, MD, USA.
2
University of Maryland School of Pharmacy, Baltimore, MD, USA.
3
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Abstract
A shortage in organs for transplantation has led to the increased use of hepatitis C (HCV) infected donor organs for solid organ transplant recipients infected with HCV. However, the donor HCV genotype is not routinely checked or known prior to transplant. Here, we report 4 cases of genotype conversion after transplantation in patients receiving HCV infected donor organs. This change in genotype may potentially impact HCV progression as well as treatment choice for these patients.