The summaries are free for public
use. The Chronic Liver Disease
Foundation will continue to add and
archive summaries of articles deemed
relevant to CLDF by the Board of
Trustees and its Advisors.
Abstract Details
Hepatitis C and recurrent treatment-resistant acute ischemic stroke
Saxsena A, Tarsia J, Dunn C, Aysenne A, Shah B, Moore DF. Proc (Bayl Univ Med Cent). 2013 Apr;26(2):182-4.
Source
Department of Neurology (Saxsena, Tarsia, Dunn, Aysenne) and Department of Radiology (Shah), Tulane University Medical Center, New Orleans, Louisiana; and the Baylor Neuroscience Center, Baylor University Medical Center at Dallas (Moore).
Abstract
Since the introduction of recombinant tissue plasminogen activator and thrombolysis, acute ischemic stroke has become a treatable disorder if the patient presents within the 4.5-hour time window. Typically, sporadic stroke is caused by atherosclerotic disease involving large or small cerebral arteries or secondary to a cardioembolic source often associated with atrial fibrillation. In the over-65-year age group, more rare causes of stroke, such as antiphospholipid syndromes, are unusual; such stroke etiologies are mostly seen in a younger age group (<55 years). Here we describe acute ischemic stroke in three patients >65 years with hepatitis C-associated antiphospholipid antibodies. We suggest that screening for antiphospholipid disorders in the older patient might be warranted, with potential implications for therapeutic management and secondary stroke prevention.