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Abstract Details
Efficacy and safety of rituximab in the treatment of vasculitic leg ulcers associated with hepatitis C virus infection
Bonilla-Abadía F, Echeverri AF, Izquierdo JH, Cañas F, Cañas CA. Case Report Rheumatol. 2012;2012:923897. doi: 10.1155/2012/923897. Epub 2012 Dec 16.
Source
Rheumatology Unit, Fundación Valle del Lili, ICESI University, Cali, Colombia.
Abstract
Vasculitic leg ulcers are a cutaneous manifestation of hepatitis C virus (HCV) infection often associated with cryoglobulinemia. Their treatment is difficult and is based on steroids and immunosuppressive drugs with an erratic response and a high probability of adverse reaction. We report three patients with vasculitic leg ulcers associated with hepatitis C virus infection who were treated successfully with rituximab. The pain control and healing were achieved quickly. No adverse effects with rituximab in these patients were presented.