Author information
1
Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Italy.
2
Division of Hepatology, S. Camillo Hospital, Rome, Italy.
3
Division of Nuclear Medicine, IFO Regina Elena National Cancer Institute, Rome, Italy.
4
Division of Interventional Radiology, IFO Regina Elena National Cancer Institute, Rome, Italy.
5
Division of Interventional Radiology, S. Camillo Hospital, Rome, Italy.
6
Division of Hepatology and Infectious Disease, National Institute for Infectious Disease "L. Spallanzani", Rome, Italy.
7
Anesthesiology and Intensive Care Unit, National Institute for Infectious Disease "L. Spallanzani", Rome, Italy.
8
Vascular and Interventional Radiology Unit, Department of Radiological, Oncological and Anatomo-pathological Sciences, Sapienza University of Rome, Rome, Italy.
Abstract
Liver transplantation (LT) for hepatocellular carcinoma (HCC) within the Milan criteria (MC) is nowadays a curative procedure. Yttrium-90 microspheres radioembolization (Y90-RE) has shown to be an effective and safe treatment of primary liver tumors. The aim of this work is to offer a view on the publications which report on the use of Y90-RE as bridge or downstaging prior to LT. Twenty articles have been considered for this world review. About 178 LT in patients were treated with Y90-RE prior to LT. Most of patients had a downstaging strategy. In all series alpha-fetoproteins decreased between Y90-RE and LT. Therefore, Y90-RE may have an important role in the bridge and downstaging treatments.