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Abstract Details
Hepatocellular carcinoma in the era of immunotherapy
Sim HW1, Knox J2. Curr Probl Cancer. 2017 Nov 14. pii: S0147-0272(17)30110-1. doi: 10.1016/j.currproblcancer.2017.10.007. [Epub ahead of print]
Author information
1
Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada. Electronic address: Hao-Wen.Sim@uhn.ca.
2
Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
Abstract
Hepatocellular carcinoma is a common malignancy which usually emerges on a background of chronic liver disease. Unfortunately, with contemporary management, patients with advanced hepatocellular carcinoma have few treatment options, and prognosis is poor. The emergence of immunotherapy has afforded new therapeutic opportunities. This article reviews the clinical evidence for immunotherapy in advanced hepatocellular carcinoma and presents ideas for future drug development.