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Abstract Details
A Bidirectional Association Between Obstructive Sleep Apnea and Metabolic-Associated Fatty Liver Disease
Endocrinol Metab Clin North Am. 2023 Sep;52(3):509-520.doi: 10.1016/j.ecl.2023.01.006. Epub 2023 Feb 26.
2Department of Thoracic Medicine, Cairns Hospital, Cairns, Queensland, Australia.
Abstract
Obesity is considered a twentieth-century epidemic and is a growing concern among health professionals. Obesity and its complications contribute to multiple chronic illnesses, such as type 2 diabetes (T2D), metabolic syndrome, obstructive sleep apnea (OSA), malignancy, and cardiovascular and liver diseases. In the last two decades, a bidirectional association between OSA and metabolic-associated fatty liver disease (MAFLD), independent of obesity, has been established. Both conditions have similar risk factors and metabolic comorbidities that may imply a common disease pathway. This review compiles the evidence and delineates the relationship between OSA and MAFLD from a clinical and diagnostic aspect.