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Abstract Details
Liver fibrosis for the dermatologist: a review
Clin Exp Dermatol. 2023 Mar 22;48(4):303-309. doi: 10.1093/ced/llac083.
1Departments of Dermatology, Portsmouth Hospitals University NHS Trust, UK.
2Departments of Gastroenterology and Hepatology, Portsmouth Hospitals University NHS Trust, UK.
Abstract
Methotrexate-induced liver fibrosis is not a well-defined pathology, and many of the reported cases can instead be classified as nonalcoholic fatty liver disease by current diagnostic criteria, which is particularly common in the psoriasis cohort. Liver fibrosis usually takes many years to progress; therefore, screening for liver fibrosis should be done no more regularly than annually at the very most in dermatology practice. An algorithm is presented about how to investigate abnormal liver blood tests and screening tools for liver fibrosis are compared.