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Abstract Details
Hepatocellular Carcinoma
Crit Care Nurs Clin North Am. 2022 Sep;34(3):289-301.doi: 10.1016/j.cnc.2022.04.004. Epub 2022 Jul 20.
1Central Virginia Veterans Affairs Medical Center, 1201 Broad Rock Blvd (111N), Richmond, VA 23249, USA. Electronic address: Hochong.gilles@va.gov.
2Central Virginia Veterans Affairs Medical Center, 1201 Broad Rock Blvd (111N), Richmond, VA 23249, USA.
Abstract
Hepatocellular carcinoma (HCC) is a primary liver malignancy commonly encountered in the setting of chronic liver disease and cirrhosis. Survival in HCC is determined by the ABCs: (A) anatomic stage; (B) biologic grade; and (C) cirrhosis severity. Improvement of imaging techniques permits clinicians to accurately diagnose HCC without biopsy confirmation. Advances in surgical and therapeutic options have improved treatment response and survival. Surgical resection, liver transplant, and thermal ablation in selected patients can potentially cure HCC. Noncurative approaches including intraarterial, radiation, and systemic therapies aim to palliate or slow the progression of disease. Management of HCC is complex, and the choice of treatment approach is enhanced by multidisciplinary consensus, including a liver transplant center.