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Abstract Details
Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease
J Clin Med. 2022 Jun 16;11(12):3477. doi: 10.3390/jcm11123477.
1Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy.
2Net4Science Academic Spin-Off, University "Magna Graecia", 88100 Catanzaro, Italy.
3Associazione CRISEA-Centro di Ricerca e Servizi Avanzati per l'Innovazione Rurale, 88055 Belcastro, Italy.
4Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
Abstract
Non-alcoholic fatty liver disease (NAFLD) presents the most common chronic liver disease globally; it is estimated that 25.24% of the world's population has NAFLD. NAFLD is a multi-factorial disease whose development involves various processes, such as insulin resistance, lipotoxicity, inflammation, cytokine imbalance, the activation of innate immunity, microbiota and environmental and genetic factors. Numerous clinical studies have shown that the Mediterranean diet produces beneficial effects in NAFLD patients. The aim of this review is to summarize the beneficial effects of lycopene, a soluble pigment found in fruit and vegetables, in NAFLD.