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Abstract Details
Asian Pacific association for the study of liver (APASL) guidelines: hepatitis B virus in pregnancy
Hepatol Int. 2022 Apr;16(2):211-253. doi: 10.1007/s12072-021-10285-5.Epub 2022 Feb 3.
1Department of Hepatology and Liver Transplantation, Institute of Liver and Biliary Sciences, D1 Vasant Kunj, New Delhi, 110070, India. manojkumardm@gmail.com.
2Department of Medicine, Ziauddin University Hospital, Karachi, Pakistan.
3Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
4Botkin Infectious Diseases Hospital, Saint Petersburg, Russia.
5Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
6Department of Hepatology, Nork Clinical Hospital of Infectious Disease, Yerevan, Armenia.
7Liver Research Center, Beijing Friendship Hospital, Capital Medial University, Beijing, China.
8Department of Hepatology and Liver Transplantation, Institute of Liver and Biliary Sciences, D1 Vasant Kunj, New Delhi, 110070, India.
9Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
10Hepatopancreatobiliary Center, School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, China.
11Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
12Department of Internal Medicine and Hepatitis Research Center, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei City, Taiwan.
14Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
15Eijkman Institute for Molecular Biology, Jakarta, Indonesia.
16Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Colombo, Sri Lanka.
17Department of Gastroenterology, Yamanashi Central Hospital, Yamanashi, Japan.
18University of Tokyo, Tokyo, Japan.
19Fatima University Medical Center Manila, Manila, Philippines.
20Department of Hepatology and Liver Transplantation, Institute of Liver and Biliary Sciences, D1 Vasant Kunj, New Delhi, 110070, India. shivsarin@gmail.com.
21French Agency for Research on AIDS and Viral Hepatitis, University of Health Science, Phnom Penh, Cambodia.
22Division of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
23Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India.
24Department of Medicine, University of Melbourne, Melbourne, VIC, Australia.
25Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
26Li Shu Fan Medical Foundation Professor in Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.
27Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
28Department of Laboratory Medicine, Department of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Abstract
Hepatitis B virus (HBV) infection still remains a major public health issue in the Asia-Pacific region. Most of the burden of HBV-related disease results from infections acquired in infancy through perinatal or early childhood exposure to HBV in Asia-Pacific. Hepatitis B during pregnancy presents unique management issues for both the mother and fetus. These APASL guidelines provide a comprehensive review and recommendations based on available evidence in the literature, for the management of females with HBV infection through every stage of pregnancy and postpartum. These also address the concerns, management challenges, and required follow-up of children born to hepatitis B-positive mothers.