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Abstract Details
Hepatocellular carcinoma and food contamination: aflatoxins and ochratoxin A as a great prompter
Felizardo RJ, Câmara NO. World J Gastroenterol. 2013 Jun 28;19(24):3723-5. doi: 10.3748/wjg.v19.i24.3723.
Source
Division of Nephrology, Department of Medicine, Federal University of Sao Paulo, Sao Paulo CEP 05508-900, Brazil.
Abstract
Prolonged exposure to mycotoxins in the diet is related to cancer, among other diseases. Hepatocellular carcinoma (HCC) accounts for 70%-90% of primary liver cancers and is the third leading cause of cancer-related deaths worldwide. Secondary metabolites, like aflatoxins and ochratoxin A (OTA), produced by some fungi species stocked in an inappropriate manner are considered an important way to increase HCC incidence. Future epidemiologic studies of HCC should focus on good practices in food preparation, food storage and the consumption of OTA-containing foods.