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Abstract Details
NAFLD Cirrhosis Is Rising Among Childbearing Women and Is the Most Common Cause of Cirrhosis in Pregnancy
Clin Gastroenterol Hepatol. 2022 Feb;20(2):e315-e318. doi: 10.1016/j.cgh.2021.01.022.Epub 2021 Jan 16.
Monika Sarkar1, Maya Djerboua2, Jennifer A Flemming3
Author information
Division of Gastroenterology and Hepatology, University of California, San Francisco, San Francisco, California. Electronic address: monika.sarkar@ucsf.edu.
ICES, Queen's University, Kingston, Ontario, Canada; Division of Gastroenterology and Hepatology, Queen's University, Kingston, Ontario, Canada.
Abstract
Rates of pregnancies affected by nonalcoholic fatty liver disease (NAFLD) in the United States have nearly tripled in the last decade and NAFLD confers increased perinatal risks, such as hypertensive complications, postpartum hemorrhage, and preterm birth.1 Rates of cirrhosis in pregnancy are also rising,2 although estimates specific to NAFLD cirrhosis are lacking. Whether NAFLD cirrhosis confers differential perinatal risks than other causes of cirrhosis in pregnancy is also unknown.