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Abstract Details
Hepatocellular carcinoma: a clinical and pathological overview
Salvatore Lorenzo Renne12, Samantha Sarcognato34, Diana Sacchi3, Maria Guido34, Massimo Roncalli12, Luigi Terracciano12, Luca Di Tommaso12
Author information
1Department of Biomedical Sciences, Humanitas University, Milan, Italy.
2IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
3Department of Pathology, Azienda ULSS2 Marca Trevigiana, Treviso, Italy.
4Department of Medicine - DIMED, University of Padova, Padova, Italy.
Abstract
HCC incidence rates have been rising in the past 3 decades and by 2025 > 1 million individuals will be affected annually. High-throughput sequencing technologies led to the identification of several molecular HCC subclasses that can be broadly grouped into 2 major subgroups, each characterized by specific morphological and phenotypical features. It is likely that this increasing knowledge and a more appropriate characterization of HCC at the pathological level will impact HCC patient management.