Author information
1
Department of Medicine, Division of Gastroenterology and Hepatology, Endoscopy Unit, Alameda Health System-Highland Hospital Campus-Highland Care Pavilion 5th Floor, 1411 East 31st Street, Oakland, CA, 94602, USA.
2
Division of Gastroenterology and Hepatology, Stanford Health Care, Palo Alto, CA, USA.
3
Department of Medicine, Division of Gastroenterology and Hepatology, Endoscopy Unit, Alameda Health System-Highland Hospital Campus-Highland Care Pavilion 5th Floor, 1411 East 31st Street, Oakland, CA, 94602, USA. rowong@alamedahealthsystem.org.
Abstract
Chronic hepatitis B virus infection (HBV) continues to pose a serious global health threat in many areas of the world, particularly in sub-Saharan Africa, the Western Pacific Region and areas of Eastern Europe. Endemicity is heterogeneous within and across regions owing to variable implementation of childhood and birth-dose vaccination programs, inconsistent screening of blood products, injection drug use, and poor education initiatives. This review aims to provide comprehensive up-to-date estimates of global seroprevalence of chronic HBV across six World Health Organization (WHO) regions, noting patterns of change over time and highlighting potential region-specific barriers to the diagnosis and elimination of HBV.