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Abstract Details
Rural-Urban Geographical Disparities in Hepatocellular Carcinoma Incidence Among US Adults, 2004-2017
Am J Gastroenterol. 2021 Feb 1;116(2):401-406. doi: 10.14309/ajg.0000000000000948.
Robert J Wong12, Sammy Saab3, Peter Konyn2, Vinay Sundaram4, Mandana Khalili5
Author information
1Division of Gastroenterology and Hepatology, Veterans Affairs Palo Alto Healthcare System, Palo Alto, California, USA.
2Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA.
3Departments of Medicine and Surgery, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA.
4Department of Medicine and Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, California, USA.
5Division of Gastroenterology and Hepatology, University of California, San Francisco, San Francisco, California, USA.
Abstract
Introduction: To evaluate impact of urbanicity and household income on hepatocellular carcinoma (HCC) incidence among US adults.
Methods: HCC incidence was evaluated by rural-urban geography and median annual household income using 2004-2017 Surveillance, Epidemiology, and End Results data.
Results: Although overall HCC incidence was highest in large metropolitan regions, average annual percent change in HCC incidence was greatest among more rural regions. Individuals in lower income categories had highest HCC incidence and greatest average annual percent change in HCC incidence.
Discussion: Disparities in HCC incidence by urbanicity and income likely reflect differences in risk factors, health-related behaviors, and barriers in access to healthcare services.