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Abstract Details
Impact of bariatric surgery on clinical outcome in LOPD.
Porcino, Mattia (M);Guccione, Fabio (F);Usbergo, Cristian (C);Navarra, Giuseppe (G);Toscano, Antonio (A);Musumeci, Olimpia (O);
OBJECTIVE: This case study aimed to evaluate the safety and efficacy of sleeve gastrectomy surgery in an obese patient with Late-onset Pompe disease (LOPD) and to explore the potential role of bariatric surgery in improving clinical outcomes and promoting a more physiological body composition when dietary and physical interventions fail.
METHODS: We describe a case of an obese LOPD patient who underwent sleeve gastrectomy, with clinical follow-up conducted to monitor motor and respiratory functions, as well as patient-reported outcome measures (PROMs), over time.
RESULTS: The surgery was well-tolerated without significant complications, and prolonged stability in motor and respiratory functions was observed. Furthermore, the patient reported improvements in quality of life and PROMs following weight loss.
CONCLUSION: This case suggests that bariatric surgery, specifically sleeve gastrectomy, may be a safe and effective complementary strategy for weight loss in LOPD patients, offering benefits in functional stability, and quality of life.
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