Managing AKI Stage 1
Although there is no specific therapy to reverse AKI, a diligent search must be conducted for treatable causes.
AKI, acute kidney injury; HRS, hepatorenal syndrome
If AKI stage 1 is diagnosed, implement risk factor management, which includes the following:
Assess for one of the following scenarios:
- SCr normalizes with risk factor management: Continue to monitor.
- SCr does not normalize within 1 to 2 days, despite risk factor management: Implement the albumin challenge (albumin 1g/kg for 2 days).
- Absolute SCr > 1.5 mg/dL should expedite the use of vasoconstrictors.
If there is no resolution following the albumin challenge, refer to the HRS-AKI criteria below to diagnose HRS-AKI:
AKI, acute kidney injury; NSAIDs, nonsteroid anti-inflammatory drugs
†Increase in SCr ≥ 0.3 mg/dL from the baseline within 48 h or a percent increase in SCr of ≥ 50%, which is known or presumed to have occurred within the preceding 7 days
